Ian Sample talks to Dr David Furman, an expert on inflammation and ageing at Stanford University. He explains how chronic inflammation is affecting our health and how lifestyle choices can help us fight it. This episode has been updated from an earlier version which stated that dairy is a cause of inflammation. Current scientific evidence suggests dairy has a negligible to marginally positive impact on inflammation in humans.. Help support our independent journalism at theguardian.com/sciencepod

Why inflammation matters, and what we can do to fight it

Madeleine Finlay speaks to the Guardian’s energy correspondent, Jillian Ambrose, about how offshore windfarms are generating record profits for the crown estate, and why King Charles has asked for the money to be used for the wider public good. She also hears from economist Guy Standing about how the seabed became a source of income for the crown and what it means for our view of the oceans as ‘commons’. Help support our independent journalism at theguardian.com/sciencepod

Why are windfarms turning record profits for the crown estate?

Ian Sample speaks to the cosmologist Dr Andrew Pontzen about the European Space Agency’s Euclid mission, which hopes to uncover more about two of the universe’s most baffling components: dark energy and dark matter. Pontzen explains what the probe will be looking for and how its findings will contribute to our understanding of the structure and evolution of the cosmos. Help support our independent journalism at theguardian.com/sciencepod

Euclid: will the mission uncover the secrets of dark matter and dark energy?

Since 2020, orcas off the coast of Spain and Portugal have been ramming boats, biting rudders and, in a few cases, sinking entire vessels. Now it has been reported that a similar encounter has happened off Shetland. Madeleine Finlay speaks to marine biologist and orca expert Hanne Strager about what might be behind these incidents and where our fascination with orcas comes from This podcast was amended on 27 June 2023. An earlier version contained audio of the calls of a humpback whale, not an orca. This audio has now been removed.. Help support our independent journalism at theguardian.com/sciencepod

Why are orcas attacking boats and is the behaviour spreading?

Scientists have created synthetic human embryos using stem cells in a groundbreaking advance that sidesteps the need for eggs or sperm. Madeleine Finlay speaks to science correspondent Hannah Devlin about her world exclusive story on this development, what it could mean for medical research, and whether the ethical and regulatory classifications of these embryos are keeping pace with the science. Help support our independent journalism at theguardian.com/sciencepod

Synthetic human embryos: can the law keep pace with the science?

At the start of 2023, the UK postal service Royal Mail was hit with an ultimatum: pay $80m (£67m) or continue to have international shipments blocked. The demand came from Russian-linked hackers the LockBit group, who had infiltrated Royal Mail’s software. Royal Mail refused to pay and eventually reinstated its overseas deliveries, but the cyber-attack came at a huge cost to the company and others that depend on its service. Ransomware attacks like this one are on the rise. So too are phishing attempts, emails and texts that try to fool recipients into clicking on links that contain malware or ask for personal information. Ian Sample speaks to the Yale law professor and author Scott Shapiro about cybercrime, how attacks hack into our psychology and what individuals and governments could do to stop it. Help support our independent journalism at theguardian.com/sciencepod

Cybercrime: what does psychology have to do with phishing?

Ian Sample speaks to the Guardian’s health editor, Andrew Gregory, and Dr Roy Herbst about the world’s biggest annual gathering of oncology professionals. Each year’s event features a mass of new research, and 2023 was no exception. What were the standout advances, and could they lead to permanent changes in the way we treat, think about and live with cancer?. Help support our independent journalism at theguardian.com/sciencepod

Will new treatments change the way we view cancer for good?

Madeleine Finlay speaks to Doug Weir from the Conflict and Environment Observatory about why the collapse of the Kakhovka dam is likely to be so damaging for biodiversity, access to clean water and levels of pollution. He explains why the environment has become such a central part of the narrative and considers what this increased focus could mean for Ukraine’s eventual recovery. Help support our independent journalism at theguardian.com/sciencepod

Kakhovka dam destruction: why is Ukraine calling it ‘ecocide’?

Last week, Nasa held the first public meeting of a panel established to investigate sightings of UFOs. It came just before a whistleblower former intelligence official told the Debrief that the US government had ‘intact and partially intact’ craft of non-human origin. Ian Sample talks to Prof David Spergel, the independent chair of Nasa’s panel, about why this is happening now, what they hope to find and why there is so much stigma attached to this field. Help support our independent journalism at theguardian.com/sciencepod

Why is Nasa looking into UFOs and what has it found so far?

Ian Sample talks to Dr Rachel Clarke about her experience working in palliative care in the NHS and now with hospices in Ukraine. She tells him what dying can teach the living, what we can learn from the Covid pandemic, and reveals the anguish and defiance of trying to provide a dignified death in the midst of war. Help support our independent journalism at theguardian.com/sciencepod

‘It’s taught me everything about living’: Rachel Clarke on delivering palliative care from the NHS to Ukraine

Food allergies appear to be increasing globally, but as scientific understanding improves, some experts believe we may one day be able to eliminate them altogether. Ian Sample speaks to Dr Kari Nadeau, an allergy specialist at Harvard School of Public Health and author of the book The End of Food Allergy, to discuss why food allergies are on the rise and what we can do to prevent – and possibly even cure – them. Help support our independent journalism at theguardian.com/sciencepod

Why are food allergies on the rise and is a cure on the horizon?

Every year, the world’s leaders gather for the UN climate change conference. At Cop28, they will be faced with two stark warnings from scientists: we are likely to breach 1.5C warming above pre-industrial levels in the next five years, and we are on course to reach 2.7C of warming by the end of the century. Progress has never been more critical and this year it lies in the hands of the United Arab Emirates, a country that has plans to expand its already extensive oil and gas productions. With six months to go, Madeleine Finlay talks to environment correspondent Fiona Harvey about Cop28’s hosts and president, why this year is particularly key, and how close we are getting to irreversible climate tipping points. Help support our independent journalism at theguardian.com/sciencepod

Six months to Cop28: will the most vital summit yet make meaningful progress?

Since it was introduced to the UK in 1850, Japanese knotweed has gone from novel ornamental plant to rampant invasive species. Madeleine Finlay speaks to journalist Samanth Subramanian about the huge costs associated with finding it on a property, and Dr Sophie Hocking explains what the plant, and our attempts to control it, might be doing to the environment.. Help support our independent journalism at theguardian.com/sciencepod

Japanese knotweed: why is it so damaging and can it be stopped?

We now know that global temperatures are likely to temporarily rise by more than 1.5C above pre-industrial levels in the next five years. Breaching this crucial threshold will give humanity an insight into what the next few decades could bring. It will undoubtedly have serious consequences in all aspects of our lives, including what we eat. In the second of our special series of episodes looking at what a future world might look like, science editor Ian Sample explores how our diets could change as the Earth heats up. Ian talks to Kew’s kitchen gardener Helena Dove about climate-resilient vegetables, visits Tiziana di Costanzo’s insect farm to try mealworms and crickets, and hears from Solar Food’s CEO, Pasi Vainikka, about making food from bacteria, electricity and air. Help support our independent journalism at theguardian.com/sciencepod

What will we eat in a post-1.5C world?

A first-of-its-kind non-hormonal drug to treat hot flushes has been approved in the US. Targeting connections in the brain that change during menopause, the drug, called fezolinetant, could provide relief for those who aren’t able to take hormonal replacement therapy. Madeleine Finlay speaks to endocrinologist and menopause specialist Prof Annice Mukherjee to find out what we know about the mechanism that causes hot flushes, how this new drug works, and what it might mean for those experiencing menopause in the future.. Help support our independent journalism at theguardian.com/sciencepod

Menopause: could a new brain-based treatment cure hot flushes?

More than 40 leading scientists have resigned en masse from the editorial board of a top science journal in protest at what they describe as the ‘greed’ of the publisher. Ian Sample speaks to correspondent Hannah Devlin about the remarkably lucrative business of scientific publishing, hears from Prof Chris Chambers about what was behind the recent mass resignation, and finds out why researchers are demanding change. Help support our independent journalism at theguardian.com/sciencepod

Is it the beginning of the end for scientific publishing?

The pioneering IVF procedure known as mitochondrial donation therapy (MDT) could prevent children from being born with devastating mitochondrial diseases. Madeleine Finlay speaks to Prof Darren Griffin, an expert in genetic diseases and reproduction, about how MDT works, the ethical considerations attached, and what techniques like it could mean for the future of reproduction. Help support our independent journalism at theguardian.com/sciencepod

First UK baby born with DNA from three people: what happens next?

Psychedelic drugs have long been been used for their mind-altering effects. Now, they are making their way into western medicine as a treatment for mental health disorders. From July, psychiatrists in Australia will be able to prescribe MDMA for post-traumatic stress disorder, making it the first country in the world to recognise psychedelics as medicines. The US could soon follow, with plans for the US Food and Drug Administration to be asked for approval to treat PTSD with MDMA this year. Ian Sample speaks to correspondent Hannah Devlin about how the science behind psychedelic therapy has progressed, and hears from Prof Celia Morgan about what treatment is actually like, what we know about the risks and what’s left to learn. Help support our independent journalism at theguardian.com/sciencepod

Will psychedelic drugs transform mental health treatment?

For the first time, researchers have found a way to non-invasively translate a person’s thoughts into text. Using fMRI scans and an AI-based decoder trained on a precursor to ChatGPT, the system can reconstruct brain activity to interpret the gist of a story someone is listening to, watching or even just imagining telling. Ian Sample speaks to one of the team behind the breakthrough, the neuroscientist Dr Alex Huth, to find out how it works, where they hope to use it, and whether our mental privacy could soon be at risk. Help support our independent journalism at theguardian.com/sciencepod

How AI is making non-invasive mind reading a reality

As the planet warms, and intense heatwaves become the norm, our urban environments need a radical rethink to keep them habitable. So what do we want the cities of the future to look like? In the first of our special series of episodes looking at what a future world could look like, Madeleine Finlay speaks to author and historian Ben Wilson, Prof Jessica Davies and Prof Diane Jones Allen about how to create cities that are fairer, greener and more self-reliant.. Help support our independent journalism at theguardian.com/sciencepod

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